Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 7/20 | 0.64 |
| ▸ | PGR | P06401 | 7/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.64 |
| ▸ | AR | P10275 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321384 | 0.90 | NR3C1 (0.78) | NR3C1LMNAPGRHIF1AAR | |
| SCHEMBL11443526 | 0.87 | NR3C1 (0.68) | NR3C1LMNAPGRHIF1AAR | |
| SCHEMBL11315955 | 0.86 | HIF1A (0.66) | NR3C1LMNAPGRHIF1AAR | |
| SCHEMBL11318411 | 0.82 | HIF1A (0.60) | NR3C1LMNAPGRHIF1AAR | |
| SCHEMBL11318418 | 0.82 | HIF1A (0.60) | NR3C1LMNAPGRHIF1AAR | |
| SCHEMBL11326793 | 0.82 | HIF1A (0.60) | NR3C1LMNAPGRHIF1AAR | |
| SCHEMBL11141467 | 0.81 | NR3C1 (0.55) | NR3C1LMNAPGRHIF1AAR | |
| SCHEMBL11322896 | 0.81 | HIF1A (0.52) | NR3C1LMNAPGRHIF1AAR | |
| SCHEMBL11322898 | 0.81 | HIF1A (0.52) | NR3C1LMNAPGRHIF1AAR | |
| SCHEMBL11306422 | 0.80 | HIF1A (0.74) | NR3C1LMNAPGRHIF1AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255331-A | 3-Acetoxy-9β-11β-epoxy-dienes and the preparation of the corresponding 6α-halogen-4-ene-3-ones | PROCHEM ESTABLISHMENT (LI) | 1981-03-10 | — | — | US | disclosed |