Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.78 |
| ▸ | LMNA | P02545 | 6/20 | 0.78 |
| ▸ | PGR | P06401 | 6/20 | 0.78 |
| ▸ | AR | P10275 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315259 | 0.90 | NR3C1 (0.64) | NR3C1HIF1ALMNAPGRAR | |
| Fluocinonide SCHEMBL2962841 | 0.87 | HIF1A (1.00) | NR3C1HIF1ALMNAPGRAR | |
| Fluocinonide SCHEMBL13072779 | 0.87 | HIF1A (1.00) | NR3C1HIF1ALMNAPGRAR | |
| Fluocinonide SCHEMBL13026147 | 0.87 | HIF1A (1.00) | NR3C1HIF1ALMNAPGRAR | |
| Fluocinonide SCHEMBL13568069 | 0.87 | HIF1A (1.00) | NR3C1HIF1ALMNAPGRAR | |
| Fluocinonide SCHEMBL4262 | 0.87 | HIF1A (1.00) | NR3C1HIF1ALMNAPGRAR | |
| Fluocinonide SCHEMBL13072509 | 0.87 | HIF1A (1.00) | NR3C1HIF1ALMNAPGRAR | |
| Fluocinonide SCHEMBL2800723 | 0.87 | HIF1A (1.00) | NR3C1HIF1ALMNAPGRAR | |
| Fluocinonide SCHEMBL9338347 | 0.87 | HIF1A (1.00) | NR3C1HIF1ALMNAPGRAR | |
| SCHEMBL6245242 | 0.87 | NR3C1 (0.63) | NR3C1HIF1ALMNAPGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255331-A | 3-Acetoxy-9β-11β-epoxy-dienes and the preparation of the corresponding 6α-halogen-4-ene-3-ones | PROCHEM ESTABLISHMENT (LI) | 1981-03-10 | — | — | US | disclosed |