SCHEMBL11315380

SCHEMBL11315380

CC(C)/C(=N\O)c1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
LMNA P02545 3/20 0.42
GAA P10253 1/20 0.42
ALDH1A1 P00352 2/20 0.41
POLB P06746 2/20 0.41
MAPT P10636 1/20 0.41
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
MAPK1 P28482 2/20 0.39
SRD5A2 P31213 1/20 0.39
USP2 O75604 1/20 0.39
HPGD P15428 1/20 0.38
TSHR P16473 2/20 0.38
ALOX15 P16050 1/20 0.38
CYP3A4 P08684 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10340700 1.00 MEN1 (0.53) MEN1KMT2ALMNAGAAALDH1A1
SCHEMBL11315381 1.00 MEN1 (0.53) MEN1KMT2ALMNAGAAALDH1A1
SCHEMBL11313376 0.80 ALDH1A1 (0.46) MEN1KMT2ALMNAGAAALDH1A1
SCHEMBL11313374 0.80 ALDH1A1 (0.46) MEN1KMT2ALMNAGAAALDH1A1
SCHEMBL9799617 0.78 MEN1 (0.49) MEN1KMT2ALMNAGAAALDH1A1
SCHEMBL1237696 0.78 TRPA1 (0.44) MEN1KMT2ALMNAALDH1A1POLB
SCHEMBL1237695 0.78 TRPA1 (0.44) MEN1KMT2ALMNAALDH1A1POLB
SCHEMBL9799614 0.78 MEN1 (0.49) MEN1KMT2ALMNAGAAALDH1A1
SCHEMBL11322817 0.78 HTT (0.43) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL11322821 0.78 HTT (0.43) MEN1KMT2ALMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE30634-E INSECTICIDES SHELL OIL COMPANY (US) 1981-06-02 US disclosed
EP-0009865-A1 Process for the stereoselective synthesis of the E isomer of aryl alkyl oximes RHONE-POULENC INC. (US) 1980-04-16 EP disclosed
US-4158015-A Process for the stereoselective synthesis of the E isomer of aryl alkyl oximes MOBIL OIL CORPORATION (US) 1979-06-12 US disclosed
US-4108897-A Benzylhydroxylamine ethers SHELL OIL COMPANY (US) 1978-08-22 US disclosed
US-4079149-A INSECTICIDES SHELL OIL COMPANY (US) 1978-03-14 US disclosed