Diphenylether

Diphenylether

SCHEMBL11315604

Oc1ccccc1.Oc1ccccc1.Oc1ccccc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.84

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.84
NR1H2 P55055 1/20 0.84
BAX Q07812 1/20 0.84
TSHR P16473 1/20 0.71
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA12 O43570 1/20 0.65
GLA P06280 1/20 0.65
CA3 P07451 1/20 0.65
CA4 P22748 1/20 0.65
CA9 Q16790 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
CA14 Q9ULX7 1/20 0.65
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
ESR1 P03372 1/20 0.63
ESR2 Q92731 1/20 0.63
MAOA P21397 1/20 0.52
PARP10 Q53GL7 1/20 0.48
SRD5A2 P31213 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL27692212 1.00 LTA4H (0.84) LTA4HNR1H2BAXTSHRCA1
Diphenylether SCHEMBL1319200 1.00 LTA4H (0.84) LTA4HNR1H2BAXTSHRCA1
Diphenylether SCHEMBL21826729 1.00 LTA4H (0.84) LTA4HNR1H2BAXTSHRCA1
Phenol SCHEMBL5380064 0.95 LTA4H (0.95) LTA4HNR1H2BAXTSHRCA1
Phenol SCHEMBL636047 0.95 LTA4H (0.95) LTA4HNR1H2BAXTSHRCA1
Diphenylether SCHEMBL1246776 0.94 LTA4H (0.94) LTA4HNR1H2BAXTSHRCA1
Diphenylether SCHEMBL27805269 0.92 LTA4H (0.73) LTA4HNR1H2BAXTSHRCA1
Diphenylether SCHEMBL11756317 0.92 LTA4H (0.73) LTA4HNR1H2BAXTSHRCA1
SCHEMBL5376734 0.92 LTA4H (1.00) LTA4HNR1H2BAXTSHRCA1
Phenol SCHEMBL15732394 0.92 LTA4H (0.90) LTA4HNR1H2BAXTSHRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4267394-A SELECTIVE TO THE ORTHO POSITION, USING A COMPLEX OF BORON TRIFLUORIDE WITH A DIALKYL ETHER TO CATALYZE THE REACTION PHILLIPS PETROLEUM COMPANY (US) 1981-05-12 US disclosed