Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325603 | 0.77 | — | — | |
| SCHEMBL13188482 | 0.77 | — | — | |
| SCHEMBL11317767 | 0.76 | CYP2D6 (0.41) | MMP1MMP8GAATSHR | |
| SCHEMBL12998079 | 0.73 | — | — | |
| SCHEMBL572298 | 0.73 | — | — | |
| SCHEMBL572299 | 0.73 | — | — | |
| SCHEMBL31384511 | 0.72 | ALDH1A1 (0.47) | TSHR | |
| SCHEMBL19236705 | 0.72 | — | — | |
| SCHEMBL11314801 | 0.72 | KDM4A (0.32) | MMP1MMP2MMP9MMP8 | |
| SCHEMBL11277517 | 0.72 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254143-A | PARACITICIDES; LIVER FLUKES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-03-03 | — | — | US | disclosed |