SCHEMBL11315752

SCHEMBL11315752

CCc1nc2c(CC)cccc2s1.NS

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MAPT P10636 2/20 0.42
IDO1 P14902 1/20 0.42
MAPK1 P28482 2/20 0.42
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
TLR8 Q9NR97 2/20 0.40
TLR7 Q9NYK1 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 1/20 0.39
PKM P14618 1/20 0.39
SLC2A1 P11166 1/20 0.35
UBE2T Q9NPD8 1/20 0.35
ASIC3 Q9UHC3 1/20 0.35
CYP3A4 P08684 1/20 0.35
SLC9A1 P19634 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11834129 0.95 MEN1 (0.51) MEN1KMT2AMAPTIDO1MAPK1
Ammonia Solution, Strong SCHEMBL28528068 0.93 MEN1 (0.50) MEN1KMT2AMAPTIDO1MAPK1
SCHEMBL201618 0.83 MEN1 (0.48) MEN1KMT2AMAPTIDO1MAPK1
SCHEMBL28360022 0.81 TLR8 (0.43) MEN1KMT2AMAPTIDO1MAPK1
SCHEMBL27652219 0.80 MEN1 (0.43) MEN1KMT2AMAPTIDO1GAA
SCHEMBL28147572 0.80 KCNH2 (0.41) MEN1KMT2AMAPTMAPK1RAB9A
SCHEMBL1771923 0.79 MEN1 (0.50) MEN1KMT2AMAPTIDO1MAPK1
SCHEMBL201830 0.79 ALDH1A1 (0.61) MEN1KMT2AMAPTIDO1MAPK1
SCHEMBL11371897 0.79 GAA (0.44) MEN1KMT2AMAPTMAPK1RAB9A
SCHEMBL28355934 0.78 TLR8 (0.45) MEN1KMT2AMAPTMAPK1TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111117008-B Low-temperature-resistant ablation-resistant butadiene rubber vulcanized heat-insulating material, preparation method and application thereof 湖北航天化学技术研究所 2022-04-12 CN claimed
CN-111117008-A Low-temperature-resistant ablation-resistant butadiene rubber vulcanized heat-insulating material, preparation method and application thereof 湖北航天化学技术研究所 2020-05-08 CN claimed
CN-110564019-A rubber composition, vulcanized rubber, and preparation method and application thereof 中国石油化工股份有限公司 2019-12-13 CN claimed
CN-102443213-B Oriented carbon nanotube / polyolefin composite material and preparation method thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2014-10-22 CN claimed
CN-102816404-A Pre-dispersing rubber accelerator master batch and preparation method thereof UNIV QINGDAO SCIENCE & TECHNOLOGY 2012-12-12 CN claimed
CN-102443213-A Oriented carbon nanotube/polyolefin composite material and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2012-05-09 CN claimed
CN-101948578-B Waste rubber powder regenerant and preparation method thereof UNIV SOUTHEAST 2011-12-07 CN claimed
CN-102140253-A Special low-viscosity easy-dispersion regenerant for modified asphalt and preparation method thereof UNIV SOUTHEAST 2011-08-03 CN claimed
CN-101948578-A Waste rubber powder regenerant and preparation method thereof UNIV SOUTHEAST 2011-01-19 CN claimed
CN-101838400-A Regenerant for regenerating waste asphalt and preparation method thereof JIANGSU SUBOTE MATERIAL CO LTD 2010-09-22 CN claimed
CN-101250249-A Polypropylene resin with high flux intensity ZHEJIANG JUNER NEW MATERIAL CO (CN) 2008-08-27 CN claimed
CN-1159458-A Curable ethylene-alpha olefin-diene elastomer composition UNION CARBIDE CHEM PLASTIC (US) 1997-09-17 CN claimed
CN-111032369-B Pneumatic tire 株式会社普利司通 2022-04-15 CN disclosed
CN-111117008-B Low-temperature-resistant ablation-resistant butadiene rubber vulcanized heat-insulating material, preparation method and application thereof 湖北航天化学技术研究所 2022-04-12 CN disclosed
CN-114222840-A Steel cord/rubber composite, tire, conveyor belt, hose, and rubber crawler 株式会社普利司通 2022-03-22 CN disclosed
CN-108178852-B Rubber composition, vulcanized rubber, and preparation method and application thereof 中国石油化工股份有限公司 2021-04-09 CN disclosed
CN-101463133-A Manufacturing method and apparatus of optical material SEIKO EPSON CORP (JP) 2009-06-24 CN disclosed
CN-101250249-A Polypropylene resin with high flux intensity ZHEJIANG JUNER NEW MATERIAL CO (CN) 2008-08-27 CN disclosed
EP-0008202-B1 ANAEROBIC ADHESIVE AND/OR SEALING COMPOSITIONS AND THEIR USE ROHM AND HAAS COMPANY (US) 1982-06-16 EP disclosed
EP-0008202-A1 Anaerobic adhesive and/or sealing compositions and their use ROHM AND HAAS COMPANY (US) 1980-02-20 EP disclosed