SCHEMBL201618

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11834129	0.88	MEN1 (0.51)	MEN1KMT2AMAPTIDO1SMN1; SMN2
	Ammonia Solution, Strong SCHEMBL28528068	0.86	MEN1 (0.50)	MEN1KMT2AMAPTIDO1SMN1; SMN2
	SCHEMBL11315752	0.83	MEN1 (0.48)	MEN1KMT2AMAPTIDO1SMN1; SMN2
	SCHEMBL7469260	0.79	ALDH1A1 (0.59)	MEN1KMT2AMAPTIDO1SMN1; SMN2
	SCHEMBL6220487	0.77	MEN1 (0.55)	MEN1KMT2AMAPTIDO1SMN1; SMN2
	SCHEMBL5537888	0.77	MEN1 (0.51)	MEN1KMT2AMAPTIDO1SMN1; SMN2
	SCHEMBL12109857	0.77	MEN1 (0.51)	MEN1KMT2AMAPTIDO1SMN1; SMN2
	SCHEMBL27652219	0.77	MEN1 (0.43)	MEN1KMT2AMAPTIDO1SMN1; SMN2
	SCHEMBL1771923	0.76	MEN1 (0.50)	MEN1KMT2AMAPTIDO1SMN1; SMN2
	SCHEMBL5537891	0.76	MEN1 (0.54)	MEN1KMT2AMAPTIDO1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.