Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318170 | 0.84 | AR (0.65) | ALDH1A1LMNACES2ABCB11CYP1A2 | |
| SCHEMBL11306381 | 0.81 | TACR1 (0.63) | MAPTTP53ALDH1A1POLBTMPRSS4 | |
| SCHEMBL11305535 | 0.80 | PDK1 (0.51) | MAPTALDH1A1POLBPDK1TMPRSS4 | |
| SCHEMBL11308042 | 0.79 | PDK1 (0.50) | MAPTALDH1A1POLBPDK1TMPRSS4 | |
| SCHEMBL14853314 | 0.77 | HDAC1 (0.61) | MAPTTP53ALDH1A1POLBMEN1 | |
| SCHEMBL11879435 | 0.75 | ALDH1A1 (0.68) | MAPTALDH1A1PDK1TMPRSS4MEN1 | |
| SCHEMBL11307468 | 0.75 | AR (0.56) | MAPTALDH1A1PDK1TMPRSS4MEN1 | |
| SCHEMBL11308062 | 0.75 | KCNJ5 (0.52) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL26545921 | 0.74 | TACR1 (0.55) | MAPTTP53ALDH1A1POLBTMPRSS4 | |
| SCHEMBL11794204 | 0.74 | AR (0.52) | MAPTALDH1A1PDK1TMPRSS4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299845-A | BACTERICIDES, FUNGICIDES | SCHERING CORPORATION (US) | 1981-11-10 | — | — | US | disclosed |