SCHEMBL1131586

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1131282	1.00	FABP3 (0.45)	FABP3FABP4BTKMDM2CMKLR1
	SCHEMBL1131834	0.90	PTPN1 (0.46)	FABP3FABP4BTKMDM2CMKLR1
	SCHEMBL1131830	0.90	PTPN1 (0.46)	FABP3FABP4BTKMDM2CMKLR1
	SCHEMBL1131572	0.89	HRH3 (0.45)	FABP3FABP4BTKMDM2CMKLR1
	SCHEMBL12860084	0.87	FABP3 (0.46)	FABP3FABP4KDM4ESMN1; SMN2
	SCHEMBL1132018	0.85	FABP3 (0.46)	FABP3FABP4BTKMDM2CMKLR1
	SCHEMBL1131603	0.85	FABP3 (0.46)	FABP3FABP4BTKMDM2CMKLR1
	SCHEMBL1131599	0.85	FABP3 (0.46)	FABP3FABP4BTKMDM2CMKLR1
	SCHEMBL1131611	0.84	PTGS2 (0.43)	FABP3FABP4CMKLR1
	SCHEMBL5861842	0.84	PTGS2 (0.43)	FABP3FABP4CMKLR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.