SCHEMBL1131603

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1131599	1.00	FABP3 (0.46)	FABP3FABP4MDM2BTKALDH1A1
	SCHEMBL1131279	0.91	FABP3 (0.44)	FABP3FABP4MDM2BTKKDM4E
	SCHEMBL1131274	0.91	FABP3 (0.44)	FABP3FABP4MDM2BTKKDM4E
	SCHEMBL1132018	0.87	FABP3 (0.46)	FABP3FABP4MDM2BTKPTGS2
	SCHEMBL12860103	0.85	FABP3 (0.47)	FABP3FABP4ALDH1A1PTGS2CYP2D6
	SCHEMBL1131586	0.85	FABP3 (0.45)	FABP3FABP4MDM2BTKKDM4E
	SCHEMBL1131282	0.85	FABP3 (0.45)	FABP3FABP4MDM2BTKKDM4E
	SCHEMBL1131572	0.84	HRH3 (0.45)	FABP3FABP4MDM2BTKALDH1A1
	SCHEMBL4001179	0.83	PTGS2 (0.47)	FABP3FABP4PKMPTGS2
	SCHEMBL3883647	0.83	PTGS2 (0.47)	FABP3FABP4PKMPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.