Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.85 |
| ▸ | CA2 | P00918 | 4/20 | 0.85 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.85 |
| ▸ | CA9 | Q16790 | 3/20 | 0.85 |
| ▸ | CA3 | P07451 | 3/20 | 0.85 |
| ▸ | CA4 | P22748 | 3/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.85 |
| ▸ | CA1 | P00915 | 2/20 | 0.85 |
| ▸ | GLA | P06280 | 1/20 | 0.85 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL27899230 | 0.92 | CA12 (0.85) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL10627588 | 0.92 | CA12 (0.85) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL10974607 | 0.92 | CA12 (0.85) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL8986244 | 0.92 | CA12 (0.85) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL8857356 | 0.92 | CA12 (0.85) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL11319397 | 0.92 | CA12 (0.85) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL3723819 | 0.92 | — | — | |
| Phenol SCHEMBL1736173 | 0.92 | — | — | |
| Phenol SCHEMBL11294759 | 0.92 | CA12 (0.85) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL28282960 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778607-A | Tracking-resistant cable material and preparation method thereof | 浙江万马高分子材料集团有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-112778607-B | Tracking-resistant cable material and preparation method thereof | 浙江万马高分子材料集团有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-112778607-A | Tracking-resistant cable material and preparation method thereof | 浙江万马高分子材料集团有限公司 | 2021-05-11 | — | — | CN | disclosed |
| EP-0020867-B1 | ETHOXYLATION WITH STRONTIUM BASES | Conoco Phillips Company (US) | 1982-08-04 | — | — | EP | disclosed |
| EP-0020867-A1 | Ethoxylation with strontium bases | Conoco Phillips Company (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4223164-A | Ethoxylation with strontium bases | CONOCO, INC. (US) | 1980-09-16 | — | — | US | disclosed |