Phenol

Phenol

SCHEMBL3723819

Oc1ccccc1.[K+].[OH-]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28221861 0.92 CA12 (0.85)
Phenol SCHEMBL11319397 0.92 CA12 (0.85)
Phenol SCHEMBL28578312 0.92
Phenol SCHEMBL8857356 0.92 CA12 (0.85)
Phenol SCHEMBL8986244 0.92 CA12 (0.85)
Phenol SCHEMBL10627588 0.92 CA12 (0.85)
Phenol SCHEMBL11294759 0.92 CA12 (0.85)
Phenol SCHEMBL11316144 0.92 CA12 (0.85)
Phenol SCHEMBL1736173 0.92
Phenol SCHEMBL28182870 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5234973-A Compositions for foundry molding processes utilizing reclaimed sand ACME RESIN CORPORATION (US) 1993-08-10 US claimed
EP-0336534-B1 COMPOSITIONS FOR FOUNDRY MOLDING PROCESSES UTILIZING RECLAIMED SAND ACME RESIN CORPORATION (US) 1992-07-22 EP claimed
US-5082876-A Alkaline phenolic resin BORDEN, INC. (US) 1992-01-21 US claimed
EP-0336534-A1 Compositions for foundry molding processes utilizing reclaimed sand ACME RESIN CORPORATION (US) 1989-10-11 EP claimed
US-RE32812-E CURING REFRACTORY, POTASSIUM ALKALI PHENOLFORMALDEHYDE RESIN, AND SILANE WITH ACTIVE ESTER BORDEN (UK) LIMITED (GB) 1988-12-27 US claimed
US-RE32720-E Foundry moulds and cores BORDEN (UK) LIMITED (GB) 1988-07-26 US claimed
US-4474904-A Foundry moulds and cores BORDEN CHEMICAL, INC. NKA HEXION SPECIALTY CHEMICALS, INC. 1984-10-02 US claimed
US-4468359-A REFRACTORIES, PHENOLIC RESIN BINDER, SILANE, CURING BORDEN (UK) LIMITED (GB) 1984-08-28 US claimed
US-8227026-B2 Particles for use as proppants or in gravel packs, methods for making and using the same MOMENTIVE SPECIALTY CHEMICALS INC. (US) 2012-07-24 US disclosed
WO-2010129119-A1 PARTICLES FOR USE AS PROPPANTS OR IN GRAVEL PACKS, METHODS FOR MAKING AND USING THE SAME HEXION SPECIALTY CHEMICALS, INC. (US) 2010-11-11 WO disclosed
US-20090238988-A1 PARTICLES FOR USE AS PROPPANTS OR IN GRAVEL PACKS, METHODS FOR MAKING AND USING THE SAME ROYAL BANK OF CANADA, AS ADMINISTRATIVE AGENT (CA) 2009-09-24 US disclosed
CN-1244125-A Use of cis-hydroxyitraconazole to avoid side effects of itraconazole and hydroxyitraconazole SEPRACOR INC (US) 2000-02-09 CN disclosed
EP-0956322-A4 1999-12-15 EP disclosed
EP-0956322-A1 CORROSION INHIBITOR FOR WELLBORE APPLICATIONS Phillips Petroleum Company (US) 1999-11-17 EP disclosed
US-5082876-A Alkaline phenolic resin BORDEN, INC. (US) 1992-01-21 US disclosed
EP-0336534-A1 Compositions for foundry molding processes utilizing reclaimed sand ACME RESIN CORPORATION (US) 1989-10-11 EP disclosed
US-RE32812-E CURING REFRACTORY, POTASSIUM ALKALI PHENOLFORMALDEHYDE RESIN, AND SILANE WITH ACTIVE ESTER BORDEN (UK) LIMITED (GB) 1988-12-27 US disclosed
US-RE32720-E Foundry moulds and cores BORDEN (UK) LIMITED (GB) 1988-07-26 US disclosed
US-4474904-A Foundry moulds and cores BORDEN CHEMICAL, INC. NKA HEXION SPECIALTY CHEMICALS, INC. 1984-10-02 US disclosed
US-4468359-A REFRACTORIES, PHENOLIC RESIN BINDER, SILANE, CURING BORDEN (UK) LIMITED (GB) 1984-08-28 US disclosed