Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330897 | 0.84 | PABPC1 (0.53) | PABPC1ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL11309468 | 0.83 | PABPC1 (0.67) | PABPC1ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL11321519 | 0.83 | PABPC1 (0.52) | PABPC1ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL11316017 | 0.79 | PABPC1 (0.61) | PABPC1ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL11787732 | 0.73 | PTGS1 (0.38) | PABPC1ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL20280579 | 0.71 | PABPC1 (0.45) | PABPC1ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL260979 | 0.70 | ALDH1A1 (0.40) | PABPC1ALDH1A1TSHRMAPK1TP53 | |
| SCHEMBL11410978 | 0.69 | PABPC1 (0.37) | PABPC1MEN1KMT2ATDP1MAPT | |
| SCHEMBL11623938 | 0.68 | PABPC1 (0.36) | PABPC1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11410522 | 0.68 | MAPT (0.44) | PABPC1ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248591-A | HAIR DYES | L'OREAL (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |
| US-3977825-A | Indoanilines in keratinic fiber dye cmpositions | L'OREAL (FR) | 1976-08-31 | — | — | US | disclosed |