Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11309618 | 0.97 | SLC6A4 (0.49) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL11320663 | 0.83 | SLC6A4 (0.48) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL11313363 | 0.82 | SLC6A4 (0.48) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL11313951 | 0.82 | SLC6A4 (0.47) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL6831189 | 0.80 | OPRM1 (0.61) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| Hydrochloric Acid SCHEMBL11307266 | 0.79 | KDM1A (0.47) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL11308137 | 0.79 | SLC6A4 (0.47) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL30567205 | 0.79 | OPRM1 (0.59) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL4180702 | 0.79 | OPRM1 (0.59) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 | |
| SCHEMBL11310796 | 0.79 | ALDH1A1 (0.46) | SLC6A4SLC6A2OPRM1SLC22A1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287212-A | USEFUL AS ANALGESICS AND DIURETICS | AMERICAN HOECHST CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |