SCHEMBL11317064

SCHEMBL11317064

CCCN(CCC)c1c([N+](=O)[O-])cc(C)c(C)c1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.55
TSHR P16473 3/20 0.55
CYP3A4 P08684 2/20 0.55
MAPK1 P28482 2/20 0.55
ALDH3A1 P30838 1/20 0.43
CYP1A2 P05177 1/20 0.42
HCAR3 P49019 2/20 0.42
MAPT P10636 4/20 0.41
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 3/20 0.36
VCAM1 P19320 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8331984 0.94 CYP3A4 (0.49) TDP1TSHRCYP3A4MAPK1ALDH3A1
SCHEMBL11328343 0.91 MAPT (0.51) TDP1TSHRCYP3A4MAPK1ALDH3A1
SCHEMBL11335649 0.88 CYP1A2 (0.45) TDP1TSHRCYP3A4MAPK1ALDH3A1
SCHEMBL11522696 0.87 CYP1A2 (0.41) TDP1TSHRCYP3A4MAPK1CYP1A2
SCHEMBL11320225 0.87 TDP1 (0.43) TDP1TSHRCYP3A4MAPK1ALDH3A1
SCHEMBL11524765 0.86 MAPT (0.59) TDP1TSHRCYP3A4MAPK1ALDH3A1
SCHEMBL9751826 0.85 TDP1 (0.56) TDP1TSHRCYP3A4MAPK1ALDH3A1
SCHEMBL11323719 0.85 TSHR (0.52) TDP1TSHRCYP3A4MAPK1ALDH3A1
SCHEMBL11523364 0.85 TDP1 (0.52) TDP1TSHRCYP3A4MAPK1ALDH3A1
SCHEMBL11321924 0.83 TDP1 (0.50) TDP1TSHRCYP3A4MAPK1ALDH3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4297127-A PREEMERGENCE HERBICIDES AMERICAN CYANAMID COMPANY (US) 1981-10-27 US disclosed
US-4251264-A 4-CYANO SUBSTITUTED AMERICAN CYANAMID COMPANY (US) 1981-02-17 US disclosed
US-4166908-A SELECTIVE PREEMERGENT ACTIVITY AMERICAN CYANAMID COMPANY (US) 1979-09-04 US disclosed
US-4165231-A 2,6-Dinitroaniline herbicides AMERICAN CYANAMID COMPANY (US) 1979-08-21 US disclosed
US-4136117-A PREPARATION OF 2,6-DINITROANILINES AMERICAN CYANAMID COMPANY (US) 1979-01-23 US disclosed
US-4124639-A N-alkoxyalkyl-2,6-dinitroaniline herbicides AMERICA CYANAMID COMPANY (US) 1978-11-07 US disclosed
US-4101582-A 2,6-Dinitroaniline herbicides AMERICAN CYANAMID COMPANY (US) 1978-07-18 US disclosed
US-4025538-A 2,6-Dinitroaniline herbicides AMERICAN CYANAMID COMPANY (US) 1977-05-24 US disclosed