Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524270 | 0.87 | CYP1A2 (0.41) | CYP1A2TDP1TSHRCYP3A4MAPK1 | |
| SCHEMBL11317064 | 0.87 | TDP1 (0.55) | CYP1A2TDP1TSHRCYP3A4MAPK1 | |
| SCHEMBL11328343 | 0.84 | MAPT (0.51) | CYP1A2TDP1TSHRCYP3A4MAPK1 | |
| SCHEMBL11335649 | 0.83 | CYP1A2 (0.45) | CYP1A2TDP1TSHRCYP3A4MAPK1 | |
| SCHEMBL8331984 | 0.81 | CYP3A4 (0.49) | CYP1A2TDP1TSHRCYP3A4MAPK1 | |
| SCHEMBL10344444 | 0.80 | CYP3A4 (0.49) | CYP1A2TDP1TSHRCYP3A4MAPK1 | |
| SCHEMBL11524765 | 0.79 | MAPT (0.59) | CYP1A2TDP1TSHRCYP3A4MAPK1 | |
| SCHEMBL13202978 | 0.79 | ALDH1A1 (0.50) | CYP1A2TDP1TSHRCYP3A4MAPK1 | |
| SCHEMBL11321861 | 0.78 | CYP1A2 (0.41) | CYP1A2TDP1TSHRCYP3A4MAPK1 | |
| SCHEMBL11318911 | 0.78 | CYP1A2 (0.41) | CYP1A2TDP1TSHRCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136117-A | PREPARATION OF 2,6-DINITROANILINES | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |