Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 8/20 | 0.39 |
| ▸ | GLA | P06280 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11309628 | 0.91 | KDM4E (0.46) | ERAP1MAOAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6993046 | 0.85 | MCL1 (0.45) | ERAP1ATMMAOAKDM4EALDH1A1 | |
| SCHEMBL11309620 | 0.82 | KDM4E (0.50) | MAOAKDM4EALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL11319802 | 0.78 | KDM4E (0.48) | ERAP1ATMMAOAKDM4EALDH1A1 | |
| SCHEMBL6993346 | 0.77 | MAOA (0.59) | MAOAKDM4EALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL11308490 | 0.75 | MCL1 (0.46) | ERAP1MAOAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL11308343 | 0.73 | KDM4E (0.62) | ERAP1MAOAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL10405325 | 0.73 | MCL1 (0.44) | ERAP1ATMMAOAKDM4EALDH1A1 | |
| SCHEMBL11316334 | 0.71 | MCL1 (0.45) | ERAP1ATMMAOAKDM4EALDH1A1 | |
| SCHEMBL11253029 | 0.71 | MAOA (0.59) | MAOAKDM4EALDH1A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269851-A | 8-Aminoalkyl-4-alkylpsoralens | THOMAS C. ELDER, INC. (US) | 1981-05-26 | — | — | US | disclosed |