Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317603 | 0.87 | PTGDR2 (0.46) | PTGDR2CYP2C19PPARD | |
| SCHEMBL14565996 | 0.77 | CYP2C19 (0.49) | PTGDR2CYP2C19PPARDGLAL3MBTL1 | |
| SCHEMBL24886126 | 0.74 | PTGDR2 (0.57) | PTGDR2GLAL3MBTL1 | |
| SCHEMBL11270936 | 0.73 | RXRA (0.33) | — | |
| SCHEMBL18528838 | 0.73 | TDP1 (0.64) | PTGDR2 | |
| SCHEMBL4810585 | 0.73 | GLA (0.46) | PTGDR2CYP2C19GLAL3MBTL1 | |
| SCHEMBL3188075 | 0.73 | PTGDR2 (0.61) | PTGDR2GLAL3MBTL1 | |
| SCHEMBL4808600 | 0.72 | L3MBTL1 (0.66) | PTGDR2GLAL3MBTL1 | |
| SCHEMBL11314673 | 0.72 | PTPN1 (0.44) | PTGDR2PPARD | |
| SCHEMBL24885619 | 0.72 | PTGDR2 (0.52) | PTGDR2GLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272550-A | Omega-[4-(polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio]alkanoic acids and compounds related thereto | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| US-4199597-A | Omega-(4-polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio)alkanoic acids and compounds related thereto | SCHERING CORPORATION (US) | 1980-04-22 | — | — | US | disclosed |