Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MTOR | P42345 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HBB | P68871 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317700 | 1.00 | LMNA (0.58) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL16805382 | 1.00 | LMNA (0.58) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL2584925 | 1.00 | LMNA (0.58) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL11331733 | 1.00 | LMNA (0.58) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL16809039 | 1.00 | LMNA (0.58) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL10889330 | 0.90 | PDE4D (0.47) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL2580679 | 0.90 | LMNA (0.46) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL10889322 | 0.90 | PDE4D (0.47) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL453967 | 0.89 | LMNA (0.59) | LMNAMTORALDH1A1THRBMDM2 | |
| SCHEMBL14853910 | 0.89 | LMNA (0.59) | LMNAMTORALDH1A1THRBMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127774-A1 | COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2025-04-24 | — | — | US | claimed |
| CN-119325467-A | Compounds for labeling nucleic acids and uses thereof | 皇家学习促进学会/麦吉尔大学 | 2025-01-17 | — | — | CN | claimed |
| EP-4476206-A1 | COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2024-12-18 | — | — | EP | claimed |
| WO-2023150867-A1 | COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2023-08-17 | — | — | WO | claimed |
| US-20250127774-A1 | COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2025-04-24 | — | — | US | disclosed |
| CN-119325467-A | Compounds for labeling nucleic acids and uses thereof | 皇家学习促进学会/麦吉尔大学 | 2025-01-17 | — | — | CN | disclosed |
| EP-4476206-A1 | COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2024-12-18 | — | — | EP | disclosed |
| WO-2024163595-A1 | DEVICES AND METHODS FOR ISOLATING AND UTILIZING EXTRACELLUAR CHROMOSOMAL MOLECULES | DIMENSION GENOMICS, INC. (US) | 2024-08-08 | — | — | WO | disclosed |
| WO-2023176863-A1 | CHEMICALLY-MODIFIED OLIGONUCLEOTIDE HAVING RNAI ACTIVITY | 第一三共株式会社 | 2023-09-21 | — | — | WO | disclosed |
| WO-2023176862-A1 | siRNA FOR SUPPRESSING EXPRESSION OF TRANSFERRIN RECEPTOR-2 | 第一三共株式会社 | 2023-09-21 | — | — | WO | disclosed |
| WO-2023150867-A1 | COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2023-08-17 | — | — | WO | disclosed |
| WO-2015197655-A1 | METHODS AND PRODUCTS FROM THE REACTION OF TETRAZINES WITH NUCLEIC ACID POLYMERS BEARING ETHENYL AROMATIC GROUPS | Universität Zürich (CH) | 2015-12-30 | — | — | WO | disclosed |
| US-4267171-A | C-5 Substituted cytosine nucleosides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1981-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250127774-A1 | COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF | POLRMT, NSUN2, NSUN3 | LMNA 358/4885MTOR 4406/4885ALDH1A1 1018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.