Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311608 | 1.00 | THRB (0.50) | THRBTHRAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL11305937 | 1.00 | THRB (0.50) | THRBTHRAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL11310624 | 1.00 | THRB (0.50) | THRBTHRAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL13790299 | 0.88 | THRB (0.51) | THRBTHRAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL2054720 | 0.85 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL10300267 | 0.82 | THRB (0.55) | THRBTHRAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL19219011 | 0.81 | ALDH1A1 (0.45) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL9101231 | 0.80 | ALDH1A1 (0.74) | THRBTHRAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8778737 | 0.80 | ALDH1A1 (0.74) | THRBTHRAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9103003 | 0.80 | ALDH1A1 (0.74) | THRBTHRAALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297277-A | FUNGICIDES ANTISEPTICS | ELI LILLY AND COMPANY (US) | 1981-10-27 | — | — | US | claimed |
| US-4293486-A | ANTIFUNGAL PEPTIDES | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | claimed |
| US-4293484-A | ANTIFUNGAL PEPTIDES | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | claimed |
| US-4293489-A | ANTIFUNGAL PEPTIDES | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | claimed |
| US-4289692-A | CYCLIC PEPTIDE ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | claimed |
| EP-0031220-A1 | Derivatives of cyclic peptide nuclei | ELI LILLY AND COMPANY (US) | 1981-07-01 | — | — | EP | claimed |
| US-4297277-A | FUNGICIDES ANTISEPTICS | ELI LILLY AND COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4293484-A | ANTIFUNGAL PEPTIDES | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4293486-A | ANTIFUNGAL PEPTIDES | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4289692-A | CYCLIC PEPTIDE ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0031220-A1 | Derivatives of cyclic peptide nuclei | ELI LILLY AND COMPANY (US) | 1981-07-01 | — | — | EP | disclosed |