Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320352 | 1.00 | MAPT (0.41) | MAPTL3MBTL1MAPK1SMN1; SMN2EGFR | |
| SCHEMBL968385 | 0.87 | MAPT (0.61) | MAPTL3MBTL1MAPK1SMN1; SMN2EGFR | |
| SCHEMBL11799069 | 0.86 | TDP1 (0.50) | MAPTL3MBTL1MAPK1SMN1; SMN2EGFR | |
| SCHEMBL10728067 | 0.85 | MAPT (0.59) | MAPTL3MBTL1MAPK1SMN1; SMN2EGFR | |
| SCHEMBL11105620 | 0.79 | MEN1 (0.73) | MAPTL3MBTL1MAPK1SMN1; SMN2EGFR | |
| SCHEMBL28415295 | 0.78 | MAPT (0.50) | MAPTL3MBTL1MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL9906067 | 0.78 | MEN1 (0.40) | MAPTL3MBTL1MAPK1SMN1; SMN2EGFR | |
| SCHEMBL10734186 | 0.76 | RXFP1 (0.54) | MAPTRAB9AKMT2AALDH1A1POLB | |
| SCHEMBL11105632 | 0.75 | MAPT (0.48) | MAPTL3MBTL1MAPK1SMN1; SMN2EGFR | |
| SCHEMBL11694719 | 0.75 | FTO (0.40) | MAPTL3MBTL1MAPK1SMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304725-A | Process for producing disperse dyes | CIBA-GEIGY CORPORATION (US) | 1981-12-08 | — | — | US | disclosed |