Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604260 | 0.89 | MAOA (0.65) | RXFP1CA1CA2CA9MAOA | |
| SCHEMBL8606780 | 0.83 | MAOA (0.55) | RXFP1CA1CA2CA9MAOA | |
| SCHEMBL11423840 | 0.81 | ALDH1A1 (0.58) | RXFP1CA1CA2CA9MAOA | |
| SCHEMBL8603596 | 0.79 | S100A4 (0.50) | RXFP1CA1CA2CA9MAOA | |
| SCHEMBL10488070 | 0.78 | MAOA (0.63) | MAOACASP3ALDH1A1HPGDKDM4E | |
| SCHEMBL11318323 | 0.76 | MAPT (0.41) | RXFP1ALDH1A1POLBMAPTRAB9A | |
| SCHEMBL11320352 | 0.76 | MAPT (0.41) | RXFP1ALDH1A1POLBMAPTRAB9A | |
| SCHEMBL11847585 | 0.76 | MEN1 (0.58) | CA2CA9CASP3ALDH1A1HPGD | |
| SCHEMBL6370986 | 0.76 | MAOA (0.77) | RXFP1MAOACASP3ALDH1A1HPGD | |
| SCHEMBL1601224 | 0.73 | RXFP1 (0.58) | RXFP1CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4657707-A | REACTING A HALOGENATED ANTHRAQUINONE, NAPHTHOQUINONE OR PHENOL WITH CONCENTRATED SULFURIC ACID AND AN ALDEHYDE | CIBA-GEIGY CORPORATION (US) | 1987-04-14 | — | — | US | disclosed |