Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498696 | 0.84 | GAA (0.50) | GAAALOX5TAAR1TSHRMAPT | |
| SCHEMBL5931188 | 0.71 | — | — | |
| SCHEMBL6952454 | 0.69 | KDM4E (0.56) | ALOX5MAPTHTTALOX15KDM4E | |
| SCHEMBL9376259 | 0.68 | GFER (0.56) | GAATAAR1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL11318602 | 0.68 | KDM4E (0.35) | TSHRMAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10501644 | 0.67 | ALOX5 (0.51) | ALOX5MAPTHTTKDM4ETP53 | |
| SCHEMBL28948440 | 0.66 | KDM4E (0.51) | ALOX5MAPTGFERHTTMEN1 | |
| SCHEMBL733240 | 0.66 | — | — | |
| SCHEMBL11669014 | 0.66 | ALOX5 (0.46) | ALOX5TSHRMAPTSMN1; SMN2HTT | |
| SCHEMBL8816431 | 0.66 | GAA (1.00) | GAATAAR1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4295848-A | Composition for hair dyeing which contains a para base and an ortho base | L'OREAL (FR) | 1981-10-20 | — | — | US | disclosed |
| US-4268264-A | ORTHO PRECURSORS SELECTED FROM AROMATIC DIAMINES, AMINOPHENOL, DIPHENOL, AND PHENYLENEDIAMINE | L'OREAL (FR) | 1981-05-19 | — | — | US | disclosed |