Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790031 | 0.77 | TSHR (0.52) | MAPTTSHRSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8634675 | 0.77 | TSHR (0.56) | ALOX5MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL30923537 | 0.77 | ALOX5 (0.47) | ALOX5MAPTTP53HTTKDM4E | |
| SCHEMBL6952454 | 0.75 | KDM4E (0.56) | ALOX5MAPTTP53HTTKDM4E | |
| SCHEMBL8629960 | 0.74 | ALOX5 (0.42) | ALOX5MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL9215401 | 0.72 | HDAC1 (0.60) | TSHRSMN1; SMN2HTTALDH1A1HDAC1 | |
| SCHEMBL918512 | 0.72 | NR3C2 (0.56) | TSHRSMN1; SMN2HTTALDH1A1HDAC1 | |
| SCHEMBL28948440 | 0.71 | KDM4E (0.51) | ALOX5MAPTTP53HTTKDM4E | |
| SCHEMBL733240 | 0.71 | — | — | |
| SCHEMBL16523570 | 0.71 | TSHR (0.51) | MAPTTSHRSMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52153928-A | — | — | None | — | — | JP | disclosed |
| JP-S52153928-A | PREPARATION OF ORGANIC COMPOUNDS | YOSHITOMI PHARMACEUT IND LTD | 1977-12-21 | — | — | JP | disclosed |