Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11419540 | 0.89 | ALDH1A1 (0.36) | ALDH1A1ATMEGFRKMT2AMAPT | |
| SCHEMBL11491153 | 0.82 | GAA (0.38) | ALDH1A1ATMSIRT2EGFRKMT2A | |
| SCHEMBL10826403 | 0.80 | EGFR (0.34) | ALDH1A1ATMEGFRKMT2AMAPT | |
| SCHEMBL11495396 | 0.80 | TDP1 (0.36) | ALDH1A1ATMEGFRKMT2AMAPT | |
| SCHEMBL11491468 | 0.78 | ESR1 (0.37) | ALDH1A1SIRT2EGFRKMT2AMAPT | |
| SCHEMBL4003918 | 0.75 | ALDH1A1 (0.43) | ALDH1A1EGFRKMT2AMAPTBACE1 | |
| SCHEMBL11491831 | 0.72 | KMT2A (0.36) | ALDH1A1EGFRKMT2AMAPTBACE1 | |
| SCHEMBL1154122 | 0.71 | MAPT (0.38) | ALDH1A1ATMEGFRKMT2AMAPT | |
| SCHEMBL1146263 | 0.70 | EGFR (0.38) | ALDH1A1ATMEGFRKMT2AMAPT | |
| SCHEMBL11491155 | 0.70 | BACE1 (0.34) | ALDH1A1SIRT2EGFRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222958-A | HAIR DYES | L'OREAL (FR) | 1980-09-16 | — | — | US | claimed |
| US-4295848-A | Composition for hair dyeing which contains a para base and an ortho base | L'OREAL (FR) | 1981-10-20 | — | — | US | disclosed |
| US-4268264-A | ORTHO PRECURSORS SELECTED FROM AROMATIC DIAMINES, AMINOPHENOL, DIPHENOL, AND PHENYLENEDIAMINE | L'OREAL (FR) | 1981-05-19 | — | — | US | disclosed |