Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20288318 | 0.84 | ALDH1A1 (0.37) | TDP1ALDH1A1THRBRECQLALOX15 | |
| SCHEMBL20285756 | 0.82 | MAPT (0.42) | TDP1ALDH1A1THRBRECQLCYP3A4 | |
| SCHEMBL4003918 | 0.82 | ALDH1A1 (0.43) | TDP1ALDH1A1THRBRECQLMAPT | |
| SCHEMBL11330823 | 0.82 | ALDH1A1 (0.41) | TDP1ALDH1A1THRBRECQLCYP3A4 | |
| SCHEMBL11491153 | 0.82 | GAA (0.38) | TDP1ALDH1A1THRBRECQLMAPT | |
| SCHEMBL11491831 | 0.82 | KMT2A (0.36) | TDP1ALDH1A1THRBRECQLCYP3A4 | |
| SCHEMBL11491468 | 0.80 | ESR1 (0.37) | TDP1ALDH1A1CYP3A4MAPTNPC1 | |
| SCHEMBL11319263 | 0.80 | ALDH1A1 (0.34) | TDP1ALDH1A1THRBRECQLCYP3A4 | |
| SCHEMBL10826403 | 0.80 | EGFR (0.34) | TDP1ALDH1A1THRBRECQLMAPT | |
| SCHEMBL21901569 | 0.80 | KDM4E (0.45) | TDP1ALDH1A1THRBRECQLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222958-A | HAIR DYES | L'OREAL (FR) | 1980-09-16 | — | — | US | claimed |
| US-4170452-A | Dye composition containing diphenylamine and polyhydroxybenzene | L'OREAL (FR) | 1979-10-09 | — | — | US | disclosed |