Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924853 | 0.77 | MEN1 (0.44) | MAPTMEN1KMT2AHSD17B10ACHE | |
| SCHEMBL3931538 | 0.72 | MAPT (0.50) | MAPTMEN1KMT2AHSD17B10ACHE | |
| SCHEMBL10507357 | 0.72 | MAPT (0.50) | MAPTMEN1KMT2AHSD17B10ACHE | |
| SCHEMBL7297638 | 0.71 | MAPT (0.48) | MAPTMEN1KMT2AHSD17B10ACHE | |
| SCHEMBL7353270 | 0.69 | ALDH1A1 (0.49) | MAPTMEN1KMT2AHSD17B10ACHE | |
| SCHEMBL11307407 | 0.69 | HSD17B10 (0.43) | MAPTMEN1KMT2AHSD17B10ACHE | |
| SCHEMBL8779825 | 0.69 | MAPT (0.50) | MAPTMEN1KMT2AHSD17B10ACHE | |
| SCHEMBL17629196 | 0.69 | MAPT (0.50) | MAPTMEN1KMT2AHSD17B10ACHE | |
| SCHEMBL6421123 | 0.67 | MAPK1 (0.52) | MAPTMEN1KMT2AHSD17B10ACHE | |
| SCHEMBL11331840 | 0.67 | MAPT (0.41) | MAPTMEN1KMT2AHSD17B10ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275184-A | HYDROSILATION OF POLYDIMETHYL SILOXANE | RHONE-POULENC INDUSTRIES (FR) | 1981-06-23 | — | — | US | disclosed |
| US-4213914-A | ADDITION-CONDENSATION COPOLYMERS | RHONE-POULENC INDUSTRIES (FR) | 1980-07-22 | — | — | US | disclosed |
| US-4147711-A | Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom | RHONE-POULENC INDUSTRIES (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4088670-A | P-(DIMETHYLVINYLSILYL-METHOXY)-BENZOYL CHLORIDE FROM DIMETHYLVINYL-CHLOROMETHYLSILANE AND A P-HYDROXYBENZOIC ACID | RHONE-POULENC INDUSTRIES (FR) | 1978-05-09 | — | — | US | disclosed |