Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353270 | 0.78 | ALDH1A1 (0.49) | MEN1MAPTKMT2AALDH1A1CES1 | |
| SCHEMBL10507357 | 0.77 | MAPT (0.50) | MEN1MAPTKMT2AALDH1A1CES1 | |
| SCHEMBL11319673 | 0.77 | MAPT (0.40) | MEN1MAPTKMT2ATGM2ALDH1A1 | |
| SCHEMBL11097893 | 0.75 | TDP1 (0.48) | MEN1MAPTKMT2AALDH1A1CES1 | |
| SCHEMBL6691324 | 0.74 | ALDH1A1 (0.53) | MEN1MAPTKMT2ATGM2ALDH1A1 | |
| SCHEMBL3931538 | 0.73 | MAPT (0.50) | MEN1MAPTKMT2AALDH1A1CES1 | |
| SCHEMBL17629196 | 0.73 | MAPT (0.50) | MEN1MAPTKMT2ATGM2ALDH1A1 | |
| SCHEMBL8779825 | 0.73 | MAPT (0.50) | MEN1MAPTKMT2AALDH1A1CES1 | |
| SCHEMBL10345825 | 0.72 | ALDH1A1 (0.39) | MAPTALDH1A1HSD17B10TSHR | |
| SCHEMBL7297638 | 0.72 | MAPT (0.48) | MEN1MAPTKMT2AALDH1A1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | disclosed |