Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21048548 | 0.88 | APP (0.37) | CYP2C19CYP1A2CYP2C9TSHRCA12 | |
| SCHEMBL15367996 | 0.83 | CA12 (0.37) | CYP2C19CYP1A2CYP2C9TSHRCA12 | |
| SCHEMBL26292935 | 0.80 | EPHX2 (0.35) | CYP2C19PTGS1PDE4ALMNASLC6A6 | |
| Sulfuric Acid SCHEMBL5180958 | 0.79 | CYP1A2 (0.48) | CYP2C19CYP1A2CYP2C9TSHRCA12 | |
| SCHEMBL19832386 | 0.78 | LMNA (0.37) | CYP2C19PTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL7722290 | 0.77 | BBOX1 (0.32) | EPHX2 | |
| Water SCHEMBL170463 | 0.76 | BBOX1 (0.31) | EPHX2 | |
| SCHEMBL1805336 | 0.75 | PTGS1 (0.45) | CYP2C19CA12CA1CA2CA9 | |
| SCHEMBL901982 | 0.74 | — | — | |
| SCHEMBL8051029 | 0.74 | TSHR (0.43) | CYP2C19CYP1A2CYP2C9TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308120-A | FREE-RADICAL POLYMERIZATION IN PRESENCE OF ULTRAVIOLET ABSORBER | ROHM GMBH (DE) | 1981-12-29 | — | — | US | disclosed |
| US-4105519-A | POLYMERIZATION METHOD USING ULTRAVIOLET LIGHT | ROHM GMBH (DE) | 1978-08-08 | — | — | US | disclosed |
| US-3948866-A | Polymerization with the aid of macromolecule having both a monomer soluble portion and suspension soluble portion | ROHM GMBH (DT) | 1976-04-06 | — | — | US | disclosed |