Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277987 | 0.92 | KDM4E (0.34) | FSCN1HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL11269830 | 0.91 | KDM4E (0.33) | FSCN1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11430940 | 0.90 | CA1 (0.32) | FSCN1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11422730 | 0.90 | FSCN1 (0.32) | FSCN1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11306907 | 0.89 | PRSS1 (0.35) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11412917 | 0.89 | CYP1A2 (0.35) | FSCN1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11431429 | 0.88 | CA1 (0.32) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11420431 | 0.88 | ALDH1A1 (0.34) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11440683 | 0.88 | CA1 (0.32) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11421476 | 0.87 | GAA (0.36) | NPC1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4219567-A | ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1980-08-26 | — | — | US | claimed |
| US-4183956-A | Method for treating gastrointestinal spasms, gastrointestinal hyperacidity and hypertensive disorders with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-01-15 | — | — | US | claimed |
| US-4283555-A | Amidinoureas | WILLIAM H. RORER, INC. (US) | 1981-08-11 | — | — | US | disclosed |
| US-4219567-A | ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1980-08-26 | — | — | US | disclosed |
| US-4183956-A | Method for treating gastrointestinal spasms, gastrointestinal hyperacidity and hypertensive disorders with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-01-15 | — | — | US | disclosed |