Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CMKLR1 | Q99788 | 6/20 | 0.42 |
| ▸ | BTK | Q06187 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131589 | 0.89 | CNR1 (0.40) | CNR1CMKLR1BTKKDM4EKMT2A | |
| SCHEMBL1131499 | 0.87 | CNR1 (0.48) | CNR1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL1132025 | 0.82 | PTPN1 (0.43) | CNR1CMKLR1BTKKDM4EKMT2A | |
| SCHEMBL1131971 | 0.82 | CMKLR1 (0.41) | CNR1CMKLR1BTKKDM4EKMT2A | |
| SCHEMBL1131969 | 0.82 | CMKLR1 (0.41) | CNR1CMKLR1BTKKDM4EKMT2A | |
| SCHEMBL1131277 | 0.80 | MDM2 (0.48) | CMKLR1BTKHTR3AHRH3 | |
| SCHEMBL1132022 | 0.79 | CMKLR1 (0.41) | CNR1CMKLR1BTKKDM4EKMT2A | |
| SCHEMBL1131947 | 0.79 | CNR1 (0.43) | CNR1CMKLR1BTKKDM4EKMT2A | |
| SCHEMBL1131696 | 0.78 | KDM4E (0.43) | CNR1CMKLR1BTKKDM4EKMT2A | |
| SCHEMBL12860095 | 0.76 | CNR1 (0.46) | CNR1CMKLR1BTKKDM4EKCNJ6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | claimed |
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |