Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMKLR1 | Q99788 | 5/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131971 | 0.91 | CMKLR1 (0.41) | CMKLR1KCNJ6KCNJ3KCNJ5CNR1 | |
| SCHEMBL1131969 | 0.91 | CMKLR1 (0.41) | CMKLR1KCNJ6KCNJ3KCNJ5CNR1 | |
| SCHEMBL1131587 | 0.90 | CMKLR1 (0.39) | CMKLR1KCNJ6KCNJ3KCNJ5CNR1 | |
| SCHEMBL1131591 | 0.90 | CMKLR1 (0.39) | CMKLR1KCNJ6KCNJ3KCNJ5CNR1 | |
| SCHEMBL1131498 | 0.88 | CNR1 (0.43) | KCNJ6KCNJ3KCNJ5CNR1HPGD | |
| SCHEMBL1131500 | 0.88 | CNR1 (0.43) | KCNJ6KCNJ3KCNJ5CNR1HPGD | |
| SCHEMBL1132025 | 0.84 | PTPN1 (0.43) | CMKLR1KCNJ6KCNJ3KCNJ5CNR1 | |
| SCHEMBL12860095 | 0.82 | CNR1 (0.46) | CMKLR1KCNJ6KCNJ3KCNJ5CNR1 | |
| SCHEMBL1131274 | 0.81 | FABP3 (0.44) | CMKLR1KCNJ6KCNJ3KCNJ5BTK | |
| SCHEMBL1131279 | 0.81 | FABP3 (0.44) | CMKLR1KCNJ6KCNJ3KCNJ5BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | claimed |
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |