Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14297683 | 0.82 | LMNA (0.59) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL13647010 | 0.78 | LMNA (0.48) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL11460831 | 0.77 | PDE10A (0.50) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL13740917 | 0.76 | TDP1 (0.39) | KMT2AALDH1A1 | |
| SCHEMBL1423315 | 0.71 | LMNA (0.46) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL6456004 | 0.71 | LMNA (0.46) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL19382689 | 0.70 | RXRA (0.34) | KMT2AMEN1 | |
| SCHEMBL11324625 | 0.70 | TLR8 (0.35) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL12036750 | 0.70 | LMNA (0.50) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL27927754 | 0.70 | LMNA (0.43) | LMNACYP1A2THRBBLMCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962485-A1 | SUBSTITUTED (PIPERIDIN-1-YL)ARYL ANALOGUES FOR MODULATING AVILACTIVITY | University Of Virginia Patent Foundation (US) | 2022-03-09 | — | — | EP | disclosed |
| US-4256738-A | BACTERICIDES, PYRIMIDINYL, QUINAZOLINYL | BOEHRINGER INGELHEIM GMBH (DE) | 1981-03-17 | — | — | US | disclosed |
| EP-0001981-A1 | 9-(Omega-heteroarylamino-alkylamino)-erythromycins, their salts, processes for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1979-05-30 | — | — | EP | disclosed |