Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 5/20 | 0.62 |
| ▸ | PGK2 | P07205 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 2/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13742442 | 0.97 | PGK1 (0.60) | PGK1PGK2SMN1; SMN2KDM4EMMP2 | |
| SCHEMBL6571879 | 0.92 | PGK1 (0.60) | PGK1PGK2SMN1; SMN2KDM4EMMP2 | |
| SCHEMBL18957741 | 0.90 | PGK1 (0.54) | PGK1PGK2SMN1; SMN2PTPRB | |
| SCHEMBL11121515 | 0.81 | PGK1 (0.52) | PGK1PGK2SMN1; SMN2KDM4EMMP2 | |
| SCHEMBL11452448 | 0.74 | PGK1 (0.48) | PGK1PGK2SMN1; SMN2KDM4EMMP2 | |
| SCHEMBL6519625 | 0.74 | PGK1 (0.48) | PGK1PGK2SMN1; SMN2KDM4EMMP2 | |
| SCHEMBL12606470 | 0.74 | PGK1 (0.48) | PGK1PGK2SMN1; SMN2 | |
| SCHEMBL11306957 | 0.72 | PGK1 (0.69) | PGK1PGK2SMN1; SMN2THRBPTPRB | |
| SCHEMBL13512948 | 0.71 | PGK1 (0.44) | PGK1PGK2SMN1; SMN2KDM4EMMP2 | |
| SCHEMBL9168205 | 0.71 | SMN1; SMN2 (0.56) | PGK1PGK2SMN1; SMN2KDM4EMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268459-A | FIREPROOFING FOR THERMOPLASTIC RESINS | AMERICAN CYANAMID COMPANY (US) | 1981-05-19 | — | — | US | disclosed |