Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.63 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.61 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.60 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.56 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.56 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.55 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | NPY4R | P50391 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619534 | 0.98 | GNRHR (0.65) | GNRHRABCC2KISS1RCXCR4PTGS1 | |
| SCHEMBL29425245 | 0.95 | GNRHR (0.62) | GNRHRABCC2KISS1RCXCR4PTGS1 | |
| SCHEMBL11793620 | 0.93 | ABCC2 (0.64) | GNRHRABCC2KISS1RCXCR4CXCL8 | |
| SCHEMBL34464914 | 0.93 | GNRHR (0.60) | GNRHRABCC2KISS1RCXCR4PTGS1 | |
| SCHEMBL30387715 | 0.92 | KISS1R (0.62) | GNRHRABCC2KISS1RCXCR4PTGS1 | |
| SCHEMBL29942618 | 0.91 | C5AR1 (0.64) | GNRHRABCC2KISS1RCXCR4PTGS1 | |
| SCHEMBL30271248 | 0.91 | C5AR1 (0.64) | GNRHRABCC2KISS1RCXCR4PTGS1 | |
| SCHEMBL29942444 | 0.91 | KISS1R (0.56) | GNRHRABCC2KISS1RCXCR4PTGS1 | |
| SCHEMBL11593491 | 0.91 | KISS1R (0.56) | GNRHRABCC2KISS1RCXCR4PTGS1 | |
| Hydrochloric Acid SCHEMBL11592749 | 0.90 | KISS1R (0.55) | GNRHRABCC2KISS1RCXCR4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272432-A | Claudogenic-interceptive nonapeptide | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |