Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ENO1 | P06733 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089559 | 0.90 | MEN1 (0.40) | LMNAMEN1HPGDTSHRBLM | |
| SCHEMBL11560406 | 0.88 | CES2 (0.44) | LMNAMEN1HPGDTSHRBLM | |
| SCHEMBL7215686 | 0.88 | CES2 (0.44) | LMNAMEN1HPGDTSHRBLM | |
| SCHEMBL11542904 | 0.85 | LMNA (0.33) | LMNAMEN1HPGDTSHRBLM | |
| SCHEMBL11542901 | 0.85 | LMNA (0.33) | LMNAMEN1HPGDTSHRBLM | |
| SCHEMBL17493330 | 0.85 | MEN1 (0.33) | LMNAMEN1HPGDTSHRBLM | |
| SCHEMBL14892056 | 0.84 | MEN1 (0.36) | LMNAMEN1HPGDTSHRBLM | |
| SCHEMBL14892410 | 0.84 | MEN1 (0.36) | LMNAMEN1HPGDTSHRBLM | |
| SCHEMBL15511187 | 0.83 | MEN1 (0.34) | LMNAMEN1HPGDTSHRBLM | |
| SCHEMBL17558775 | 0.81 | LMNA (0.33) | LMNAMEN1HPGDTSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735276-B1 | NOVEL METHOD FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF VITAMIN D ANALOGUES | LEO PHARMA AS (DK) | 2011-02-16 | — | — | EP | claimed |
| EP-4100005-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |
| CN-1938268-B | Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues | LEO PHARMA AS | 2010-06-02 | — | — | CN | disclosed |
| CN-1938268-A | Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues | LEO PHARMA AS (DK) | 2007-03-28 | — | — | CN | disclosed |