Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510541 | 0.91 | HPGD (0.49) | TDP1L3MBTL1KDM4ECYP2D6LMNA | |
| SCHEMBL23589323 | 0.83 | TDP1 (0.60) | TDP1L3MBTL1KDM4ECYP2D6LMNA | |
| SCHEMBL18637701 | 0.81 | TDP1 (0.58) | TDP1L3MBTL1KDM4ECYP2D6LMNA | |
| SCHEMBL1291152 | 0.80 | KMT2A (0.61) | KDM4ELMNAMAPTTSHRHIF1A | |
| SCHEMBL1226540 | 0.80 | RRM1 (0.38) | TDP1L3MBTL1KDM4ELMNAMAPT | |
| SCHEMBL267463 | 0.78 | LMNA (0.68) | L3MBTL1KDM4ECYP2D6LMNAMAPT | |
| SCHEMBL31243296 | 0.78 | CA1 (0.57) | KDM4ECYP2D6MAPTTSHRKMT2A | |
| SCHEMBL8303709 | 0.78 | CA1 (0.57) | KDM4ECYP2D6MAPTTSHRKMT2A | |
| SCHEMBL11785803 | 0.76 | LMNA (0.52) | TDP1L3MBTL1KDM4ECYP2D6LMNA | |
| Glycerin SCHEMBL28135671 | 0.75 | TDP1 (0.74) | TDP1L3MBTL1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454248-A | COMPRESSION OF CLOSED CELLS | THE BOEING COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| US-4141187-A | Roofing and surfacing material and method | GRAVES ROBERT J | 1979-02-27 | — | — | US | disclosed |
| US-3956241-A | CHROMIUM(III) CHELATE COMPOUND | AEROJET-GENERAL CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |