SCHEMBL1132282

SCHEMBL1132282

CCC(O)C(N)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10123410 1.00
SCHEMBL10123412 1.00
SCHEMBL10123411 1.00
SCHEMBL12493240 1.00
SCHEMBL10123413 1.00
SCHEMBL14753828 1.00
SCHEMBL14753821 0.83 LMNA (0.45)
SCHEMBL4133282 0.83 LMNA (0.45)
SCHEMBL14543846 0.83 LMNA (0.45)
SCHEMBL19672352 0.83 LMNA (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3270949-A2 INSULIN ANALOGUES CONTAINING A GLUCOSE-REGULATED CONFORMATIONAL SWITCH Case Western Reserve University (US) 2018-01-24 EP claimed
EP-1728836-B1 INK-JET INK AND METHOD FOR INKJET RECORDING CANON KK (JP) 2017-05-10 EP claimed
WO-2016149222-A2 INSULIN ANALOGUES CONTAINING A GLUCOSE-REGULATED CONFORMATIONAL SWITCH CASE WESTERN RESERVE UNIVERSITY (US) 2016-09-22 WO claimed
US-20230399373-A1 MOLECULAR DESIGNS OF GLUCOSE-RESPONSIVE AND GLUCOSE-CLEAVABLE INSULIN ANALOGUES THE TRUSTEES OF INDIANA UNIVERSITY 2023-12-14 US disclosed
EP-4003426-A1 INSULIN ANALOGUES WITH GLUCOSE REGULATED CONFORMATIONAL SWITCH Thermalin Inc. (US) 2022-06-01 EP disclosed
WO-2021022116-A1 INSULIN ANALOGUES WITH GLUCOSE REGULATED CONFORMATIONAL SWITCH THERMALIN INC. (US) 2021-02-04 WO disclosed
US-20200268686-A1 SPHINGOID COMPOUNDS FOR PROPHYLAXIS AND/OR THERAPY OF A VIRAL INFECTION Harbins Ruhr Bioscience, Inc. 2020-08-27 US disclosed
CN-105009223-B Method for removing radioactive iodine, radioactive cesium, and hydrophilic resin composition for removal 大日精化工业株式会社 2017-04-12 CN disclosed
CN-103804123-B The synthetic method of a kind of fingolimod hydrochloride and intermediate thereof 成都弘达药业有限公司 2016-12-07 CN disclosed
US-20130231305-A1 Method of Modulating Protein 14-3-3 Functionality By Facilitating or Inhibiting Phosphorylation MEDVET SCIENCE PTY. LTD. (AU) 2013-09-05 US disclosed
US-8507673-B2 Process for preparing 5,7 diaminopyrazolo [1,5-A] pyrimidine compounds EMORY UNIVERSITY (US) 2013-08-13 US disclosed
US-4113880-A ANTIALLERGENS THE UPJOHN COMPANY (US) 1978-09-12 US disclosed
US-4091011-A PROPHYLACTIC ANTIANAPHYLACTICS, ANTIALLERGENS THE UPJOHN COMPANY (US) 1978-05-23 US disclosed
US-4069332-A 5,5'-PHENYLENEBIS(1,2,4-OXADIAZOLE-3-CARBOXYLIC ACIDS OR ESTERS) THE UPJOHN COMPANY (US) 1978-01-17 US disclosed
US-4067995-A ANTIALLERGENS; N,N-(CYANO-PHENYLENE)-DIOXAMIC ACID DERIVATIVES THE UPJOHN COMPANY (US) 1978-01-10 US disclosed
US-4066769-A ANTIALLERGINS THE UPJOHN COMPANY (US) 1978-01-03 US disclosed
US-4061791-A Anti-allergic oxanilate compounds THE UPJOHN COMPANY (US) 1977-12-06 US disclosed
US-4017538-A ANTIALLERGY, ANTIANAPHYLACTIC THE UPJOHN COMPANY (US) 1977-04-12 US disclosed
US-3982006-A PROPHYLAXIS, ANTIALLERGY, ANTIANAPHYLACTIC THE UPJOHN COMPANY (US) 1976-09-21 US disclosed
US-3962308-A Process for converting esters to amine salts THE UPJOHN COMPANY (US) 1976-06-08 US disclosed