SCHEMBL4133282

SCHEMBL4133282

CCC(O)C(O)C(N)CO

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.45
CYP2D6 P10635 4/20 0.45
MAPT P10636 4/20 0.45
SPHK1 Q9NYA1 3/20 0.45
GMNN O75496 3/20 0.45
POLB P06746 3/20 0.45
BLM P54132 3/20 0.45
CETP P11597 3/20 0.45
UBE2N P61088 3/20 0.45
THPO P40225 2/20 0.45
TP53 P04637 2/20 0.45
CYP1A2 P05177 2/20 0.45
KDM4E B2RXH2 2/20 0.45
MTOR P42345 1/20 0.45
CYP3A4 P08684 1/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14753821 1.00 LMNA (0.45) LMNACYP2D6MAPTSPHK1GMNN
SCHEMBL12009794 1.00 LMNA (0.45) LMNACYP2D6MAPTSPHK1GMNN
SCHEMBL14543846 1.00 LMNA (0.45) LMNACYP2D6MAPTSPHK1GMNN
SCHEMBL10123410 0.83
SCHEMBL16367524 0.83 TSHR (0.35) LMNACYP2D6MAPTSPHK1GMNN
SCHEMBL12493240 0.83
SCHEMBL14753828 0.83
SCHEMBL1132282 0.83
SCHEMBL10123411 0.83
SCHEMBL10123412 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372207-A1 CARBONATED AEROSOL EXTERNAL PREPARATION FOR SKIN KAO CORPORATION (JP) 2023-11-23 US disclosed
US-20230372207-A1 CARBONATED AEROSOL EXTERNAL PREPARATION FOR SKIN KAO CORPORATION (JP) 2023-11-23 US disclosed
US-11820789-B2 Glycosylated sphingoid bases and production thereof CARBOCODE S.A. (PT) 2023-11-21 US disclosed
US-11730686-B2 Cosmetic skincare compositions THE BOOTS COMPANY PLC (GB) 2023-08-22 US disclosed
US-11730686-B2 Cosmetic skincare compositions THE BOOTS COMPANY PLC (GB) 2023-08-22 US disclosed
WO-2020250966-A1 EMULSION COMPOSITION 花王株式会社 2020-12-17 WO disclosed
US-9694076-B2 Vesicle composition KAO CORPORATION (JP) 2017-07-04 US disclosed
US-9694076-B2 Vesicle composition KAO CORPORATION (JP) 2017-07-04 US disclosed
US-20160166698-A1 VESICLE COMPOSITION KAO CORPORATION (JP) 2016-06-16 US disclosed
US-9278059-B2 Emulsified cosmetic composition KAO CORPORATION (JP) 2016-03-08 US disclosed
US-20120295989-A1 OIL-BASED COMPOSITION KAO CORPORATION (JP) 2012-11-22 US disclosed
US-8178584-B2 Sphingosines, fatty acid, and oil; improved stability and feel to skin KAO CORPORATION (JP) 2012-05-15 US disclosed
US-20120108661-A1 EMULSIFIED COMPOSITION KAO CORPORATION (JP) 2012-05-03 US disclosed
US-20110263714-A1 Reverse Vesicle KAO CORPORATION (JP) 2011-10-27 US disclosed
US-20110165658-A1 PHOTOSYNTHETIC MICROORGANISMS ENRICHED IN SELENIUM USING SELENOHYDROXY ACID COMPOUNDS, USED THEREOF IN NUTRITION, COSMETICS AND PHARMACY ECO SOLUTION (FR) 2011-07-07 US disclosed
US-20110151545-A1 NON-PHOTOSYNTHETIC MICRO-ORGANISMS ENRICHED WITH ORGANIC SELENIUM FROM SELENO-HYDROXYACID COMPOUNDS AND APPLICATIONS THEREOF IN THE FIELDS OF NUTRITION, COSMETICS AND PHARMACUEUTICALS TETRAHEDRON 2011-06-23 US disclosed
US-20100311836-A1 OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION KAO CORPORATION (JP) 2010-12-09 US disclosed
US-7846969-B2 Ceramide emulsions KAO CORPORATION (JP) 2010-12-07 US disclosed
EP-1778706-B1 NEW SELENOHYDROXY ACIDS AND THEIR DERIVATIVES: APPLICATIONS IN NUTRITION, COSMETICS AND PHARMACEUTICS TETRAHEDRON (FR) 2009-07-08 EP disclosed
US-7381416-B2 Selenohydroxy acids and their derivatives, applications in nutrition, cosmetics and pharmaceutics TETRAHEDRON SAS (FR) 2008-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820789-B2 Glycosylated sphingoid bases and production thereof UGCG, CERT1, SGMS1 LMNA 1301/4885CYP2D6 3308/4885MAPT 4396/4885
US-20230372207-A1 CARBONATED AEROSOL EXTERNAL PREPARATION FOR SKIN CERT1, CERS2, SGMS2 LMNA 390/4885CYP2D6 4725/4885MAPT 1954/4885
US-20120295989-A1 OIL-BASED COMPOSITION SGMS1, SGMS2, F12 LMNA 244/4885CYP2D6 3781/4885MAPT 3930/4885
US-20160166698-A1 VESICLE COMPOSITION SGMS1, EXOSC10, SGMS2 LMNA 3672/4885CYP2D6 3089/4885MAPT 3843/4885
US-20100311836-A1 OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION CERT1, SGMS1, DEGS1 LMNA 600/4885CYP2D6 2053/4885MAPT 4411/4885
US-20120108661-A1 EMULSIFIED COMPOSITION CERT1, S1PR4, S1PR3 LMNA 1152/4885CYP2D6 1746/4885MAPT 2740/4885
US-20110263714-A1 Reverse Vesicle SGMS1, EXOSC10, SGMS2 LMNA 380/4885CYP2D6 3441/4885MAPT 4614/4885
US-11730686-B2 Cosmetic skincare compositions SPHK1, SPHK2, S1PR2 LMNA 1281/4885CYP2D6 4815/4885MAPT 2412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.