Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.68 |
| ▸ | ESR1 | P03372 | 2/20 | 0.68 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308699 | 0.85 | LMNA (0.68) | PGRADORA3SLC6A3KCNH2LMNA | |
| SCHEMBL11324394 | 0.83 | LMNA (0.66) | PGRADORA3SLC6A3KCNH2LMNA | |
| SCHEMBL14340044 | 0.82 | CYP1A2 (0.85) | PGRADORA3SLC6A3KCNH2LMNA | |
| SCHEMBL11636166 | 0.82 | ALOX15 (0.77) | PGRADORA3SLC6A3KCNH2LMNA | |
| SCHEMBL11322954 | 0.82 | LMNA (0.73) | PGRADORA3SLC6A3KCNH2LMNA | |
| Butoconazole SCHEMBL44237 | 0.81 | CYP1A2 (1.00) | PGRADORA3SLC6A3KCNH2LMNA | |
| Butoconazole SCHEMBL44238 | 0.81 | CYP1A2 (1.00) | PGRADORA3SLC6A3KCNH2LMNA | |
| Butoconazole SCHEMBL44239 | 0.81 | CYP1A2 (1.00) | PGRADORA3SLC6A3KCNH2LMNA | |
| SCHEMBL11308773 | 0.80 | ALOX15 (0.68) | PGRADORA3SLC6A3KCNH2LMNA | |
| SCHEMBL10927970 | 0.80 | ESR1 (0.43) | PGRADORA3SLC6A3KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272545-A | FUNGICIDES, BACTERICIDE, ANTIPROTOZOA, SPERMATOCIDE | SYNTEX (U.S.A.) INC. (US) | 1981-06-09 | — | — | US | disclosed |