Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240386 | 0.83 | TDP1 (0.57) | TDP1POLBHTTPTGS2CYP19A1 | |
| SCHEMBL2434154 | 0.81 | SMN1; SMN2 (0.62) | TDP1POLBHTTPTGS2CYP19A1 | |
| SCHEMBL3071086 | 0.80 | TDP1 (0.57) | TDP1POLBHTTPTGS2CYP19A1 | |
| SCHEMBL29800437 | 0.80 | TDP1 (0.57) | TDP1POLBHTTPTGS2CYP19A1 | |
| SCHEMBL5188245 | 0.80 | TDP1 (0.61) | TDP1POLBHTTPTGS2CYP19A1 | |
| SCHEMBL23833731 | 0.80 | TDP1 (0.57) | TDP1POLBHTTPTGS2CYP19A1 | |
| SCHEMBL29451712 | 0.78 | ALDH1A1 (0.66) | TDP1POLBHTTPTGS2CYP19A1 | |
| SCHEMBL11327832 | 0.76 | L3MBTL1 (0.58) | ALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1259655 | 0.76 | TDP1 (0.64) | TDP1POLBHTTPTGS2CYP19A1 | |
| SCHEMBL11330213 | 0.75 | SMN1; SMN2 (0.55) | HTTALDH1A1SMN1; SMN2PKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260552-A | INSECTICIDES, HERBICIDES | UNIROYAL, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4160846-A | Method for controlling insects with tetrasubstituted organotin compounds | UNIROYAL, INC. (US) | 1979-07-10 | — | — | US | disclosed |