Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311695 | 0.79 | POLB (0.49) | HPGDPOLB | |
| SCHEMBL29966079 | 0.79 | KDM4E (0.45) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL78143 | 0.79 | KDM4E (0.45) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11318287 | 0.78 | ABCB1 (0.44) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5709540 | 0.77 | HDAC8 (0.50) | MMP3HDAC8PLK1ALDH1A1HPGD | |
| SCHEMBL145153 | 0.76 | HDAC8 (0.69) | MMP3HDAC8PLK1ALDH1A1HPGD | |
| SCHEMBL11693917 | 0.71 | TMPRSS4 (0.47) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11322546 | 0.71 | TDP1 (0.50) | HDAC8ALDH1A1POLBKMT2AGAA | |
| SCHEMBL9714333 | 0.70 | ABCB1 (0.55) | MMP3HDAC8PLK1POLB | |
| SCHEMBL11480053 | 0.70 | NR4A1 (0.52) | MMP3HDAC8PLK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035325-A | ANTIMONY, SUBSTITUTED HYDRAZINE OR 3-AMINO-1,2,4-TRIAZOLE AMIDE ION | STANDARD OIL COMPANY (INDIANA) (US) | 1977-07-12 | — | — | US | claimed |
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-4038247-A | STABILIZING POLYOLEFINS WITH DIACYL DIHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |
| US-4035325-A | ANTIMONY, SUBSTITUTED HYDRAZINE OR 3-AMINO-1,2,4-TRIAZOLE AMIDE ION | STANDARD OIL COMPANY (INDIANA) (US) | 1977-07-12 | — | — | US | disclosed |
| US-3994987-A | Metal deactivators as adhesion promotors for vulcanizable elastomers to metals | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |