SCHEMBL78143

SCHEMBL78143

NNC(=O)C(=O)N(NC(=O)c1ccccc1O)C(=O)c1ccccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.45
GAA P10253 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MPO P05164 1/20 0.45
HIF1A Q16665 1/20 0.45
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
LMNA P02545 6/20 0.41
HTT P42858 5/20 0.41
HPGD P15428 5/20 0.41
HSD17B10 Q99714 5/20 0.41
NPC1 O15118 4/20 0.41
TP53 P04637 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 5/20 0.40
TSHR P16473 2/20 0.40
MAPT P10636 2/20 0.40
RAB9A P51151 3/20 0.38
L1CAM P32004 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29966079 1.00 KDM4E (0.45) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL11693917 0.87 TMPRSS4 (0.47) KDM4ESMN1; SMN2LMNAHTTHPGD
SCHEMBL11328037 0.85 KDM4E (0.47) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL11311695 0.82 POLB (0.49) KDM4EHPGDPOLB
SCHEMBL11318287 0.81 ABCB1 (0.44) SMN1; SMN2HPGDNPC1MEN1KMT2A
SCHEMBL548547 0.79 CA1 (0.47) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL11323100 0.79 MMP3 (0.49) GAASMN1; SMN2LMNAHPGDNPC1
SCHEMBL1291911 0.78 KDM4E (0.44) KDM4EGAASMN1; SMN2MPOHIF1A
SCHEMBL11604313 0.78 CSNK2A1 (0.43) KDM4ESMN1; SMN2LMNAHTTHPGD
SCHEMBL11689088 0.78 GAA (0.41) KDM4EGAASMN1; SMN2MPOHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2316 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676887-B1 Composition and process for improving heat and weathering stability of segmented polyurethane polymers CIBA SC HOLDING AG (CH) 2007-05-23 EP claimed
EP-1676887-A1 Composition and process for improving heat and weathering stability of segmented polyurethane polymers Ciba Specialty Chemicals Holding Inc. (CH) 2006-07-05 EP claimed
US-20060142441-A1 Composition and process for improving heat and weathering stability of segmented polyurethane polymers CIBA SPECIALTY CHEMICALS CORP. 2006-06-29 US claimed
EP-0108714-A1 Dibenzodioxaphosphepine and dioxaphosphocine processing stabilizers CIBA-GEIGY AG (CH) 1984-05-16 EP claimed
US-20240239989-A1 STABILIZED POLYMER RESIN SYSTEMS HAVING HETEROPOLYOXOMETALATES FOR ANTIMICROBIAL PROPERTIES AND USES THEREOF SPECIALTY OPERATIONS FRANCE (FR) 2024-07-18 US disclosed
WO-2024150714-A1 PROCESSING STABILIZER, RESIN COMPOSITION, AND ORGANIC MATERIAL STABILIZING METHOD 住友化学株式会社 2024-07-18 WO disclosed
WO-2024133667-A1 A METHOD FOR IMPROVING THE PROCESSING OF POLYETHYLENE BASF SE (DE) 2024-06-27 WO disclosed
US-12006417-B2 Additive mixture containing a particular sterically hindered amine compound and a heat reflecting interference pigment BASF SE (DE) 2024-06-11 US disclosed
US-20240174839-A1 STABILIZER MIXTURE BASF SE (DE) 2024-05-30 US disclosed
EP-4373886-A1 AN ADDITIVE MIXTURE FOR STABILIZATION OF ORGANIC MATERIAL BASF SE (DE) 2024-05-29 EP disclosed
US-20240166672-A1 PHOSPHOROUS ESTER COMPOUND, METHOD FOR PRODUCING SAME AND USE APPLICATION FOR SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-05-23 US disclosed
EP-4371988-A1 PHENOLIC COMPOUND, ORGANIC MATERIAL STABILIZER, RESIN COMPOSITION, AND METHOD FOR STABILIZING ORGANIC MATERIAL Sumitomo Chemical Company, Limited (JP) 2024-05-22 EP disclosed
US-3959413-A POLYOLEFIN STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-25 US disclosed
US-3956427-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3956298-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3944632-A Phosphoric acid anilides CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3943096-A Use of hydroxyphenylurethanes for stabilising elastomers CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3940363-A POLYMERS SANKYO COMPANY LIMITED (JA) 1976-02-24 US disclosed
US-3939175-A STABILIZER CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed