Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.69 |
| ▸ | MMP3 | P08254 | 1/20 | 0.69 |
| ▸ | PLK1 | P53350 | 1/20 | 0.67 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.59 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482553 | 0.89 | HDAC8 (0.56) | HDAC8MMP3PLK1NR4A1NR4A2 | |
| SCHEMBL808428 | 0.87 | CTSD (0.52) | HDAC8MMP3PLK1MEN1KMT2A | |
| SCHEMBL3796366 | 0.85 | HDAC8 (0.56) | HDAC8MMP3PLK1NR4A1NR4A2 | |
| SCHEMBL6635701 | 0.83 | MMP3 (0.74) | HDAC8MMP3PLK1NR4A1NR4A2 | |
| SCHEMBL1605906 | 0.83 | HDAC8 (0.74) | HDAC8MMP3PLK1NR4A1NR4A2 | |
| SCHEMBL3296572 | 0.83 | GAA (0.66) | HDAC8MMP3PLK1MEN1KMT2A | |
| SCHEMBL466508 | 0.83 | MAPT (0.52) | HDAC8MMP3PLK1MEN1KMT2A | |
| SCHEMBL7872561 | 0.82 | HDAC8 (1.00) | HDAC8MMP3PLK1NR4A1NR4A2 | |
| SCHEMBL2230679 | 0.82 | HDAC8 (1.00) | HDAC8MMP3PLK1NR4A1NR4A2 | |
| SCHEMBL29816659 | 0.82 | HDAC8 (1.00) | HDAC8MMP3PLK1NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515993-A | Interface reinforcing agent for cracking carbon black, reinforcing cracking carbon black and application thereof | 河北格林瑞特科技有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-118222016-A | Tread rubber composition for all-steel radial tire guide wheel and preparation method of tread rubber for guide wheel | 有道轮胎有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-117447399-A | Naphthalene formylhydrazine compound and preparation method and application thereof | 上海应用技术大学 | 2024-01-26 | — | — | CN | claimed |
| CN-114685933-B | Polyformaldehyde composite material and preparation method and application thereof | 江苏金发科技新材料有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-113603610-B | Naphthalene hydrazide organic gel factor and preparation method and application thereof | 上海应用技术大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116731407-A | Formula and preparation process of tire base of high-modulus low-heat-generation engineering machinery tire | 山东玲珑轮胎股份有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-116285028-A | All-steel truck radial tire base rubber composition and preparation method thereof | 江苏通用科技股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-114685933-A | Polyformaldehyde composite material and preparation method and application thereof | 江苏金发科技新材料有限公司 | 2022-07-01 | — | — | CN | claimed |
| WO-2022100629-A1 | LOW-HEAT-GENERATION, TEAR-RESISTANT RUBBER COMPOSITION FOR ENGINEERING TIRE AND PREPARATION METHOD THEREFOR | 赛轮集团股份有限公司 | 2022-05-19 | — | — | WO | claimed |
| CN-114479206-A | Low-heat-generation tear-resistant rubber composition for engineering tire and preparation method thereof | 赛轮集团股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-1411472-A | Natural rubber produced from latex and composition comprising same | BRIDGESTONE CORP (JP) | 2003-04-16 | — | — | CN | claimed |
| US-6531527-B2 | Liquid dilution after coagulation | BRIDGESTONE CORPORATION (JP) | 2003-03-11 | — | — | US | claimed |
| WO-2002102301-A2 | SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2002-12-27 | — | — | WO | claimed |
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2002-09-12 | — | — | US | claimed |
| WO-2002038667-A2 | NATURAL RUBBER PRODUCED FROM LATEX AND COMPOSITION COMPRISING THE SAME | BRIDGESTONE CORPORATION (JP) | 2002-05-16 | — | — | WO | claimed |
| US-20020035195-A1 | Viscosity-stabilizer-containing natural rubber latex and natural rubber and a production process thereof | BRIDGESTONE CORPORATION | 2002-03-21 | — | — | US | claimed |
| CN-1330083-A | Natural rubber latex and nutual rubber containing viscosity stabilizing agent and production method thereof | BRIDGESTON CORP (JP) | 2002-01-09 | — | — | CN | claimed |
| EP-0983334-A1 | ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION | Call, Krimhild (DE) | 2000-03-08 | — | — | EP | claimed |
| WO-1999001607-A2 | ENZYMATIC OXIDATION SYSTEM WITH NOVEL ENZYMATIC-EFFECT ENHANCING COMPOUNDS | CALL, KRIMHILD (DE) | 1999-01-14 | — | — | WO | claimed |
| WO-1998051772-A1 | ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION | CALL, KRIMHILD (DE) | 1998-11-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | HDAC8 290/4885MMP3 624/4885PLK1 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.