Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOA | P61586 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.36 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.36 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.36 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324116 | 0.80 | RXFP1 (0.36) | RAB9ANPC1TDP1ALDH1A1 | |
| SCHEMBL11055323 | 0.74 | ALDH1A1 (0.38) | RHOAMAPTLMNAGUCY1B2GUCY1A2 | |
| SCHEMBL28753879 | 0.67 | MAPT (0.51) | MAPTRAB9ALMNAGUCY1B2GUCY1A2 | |
| SCHEMBL2084891 | 0.64 | TTR (0.53) | MAPTLMNAGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL30663240 | 0.64 | TTR (0.47) | MAPTRAB9ALMNAMEN1NPC1 | |
| SCHEMBL28046337 | 0.62 | MAPT (0.50) | MAPTRAB9ALMNAMEN1NPC1 | |
| SCHEMBL32690191 | 0.61 | RAB9A (0.62) | MAPTRAB9ALMNAMEN1NPC1 | |
| SCHEMBL8541741 | 0.61 | ALDH1A1 (0.58) | MAPTRAB9ALMNAMEN1KMT2A | |
| SCHEMBL29098567 | 0.61 | CYP1A2 (0.54) | MAPTRAB9ALMNAMEN1NPC1 | |
| SCHEMBL7260391 | 0.60 | ALDH1A1 (0.51) | MAPTLMNAGUCY1B2GUCY1A2GUCY1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250182-A | Pharmaceutical composition containing acridone compounds and method of using same | BURROUGHS WELLCOME CO. (US) | 1981-02-10 | — | — | US | disclosed |