Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261464 | 0.84 | SRD5A1 (0.60) | SRD5A1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL29074526 | 0.82 | SRD5A1 (1.00) | SRD5A1KDM4EALDH1A1HPGDMCL1 | |
| SCHEMBL29051460 | 0.81 | SRD5A1 (0.56) | SRD5A1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL11561444 | 0.81 | SRD5A1 (0.56) | SRD5A1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL4342801 | 0.78 | KDM4E (0.67) | SRD5A1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL7825655 | 0.77 | SRD5A1 (1.00) | SRD5A1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL21631767 | 0.75 | MCL1 (0.51) | SRD5A1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL4333679 | 0.71 | SRD5A1 (0.61) | SRD5A1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL20226268 | 0.71 | GABRA1 (0.41) | SRD5A1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL3284020 | 0.71 | XPO1 (0.66) | SRD5A1KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328239-A | 8-Aminoalkylpsoralens | ELDER PHARMACEUTICALS, INC. (US) | 1982-05-04 | — | — | US | disclosed |