Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595171 | 0.89 | SMN1; SMN2 (0.40) | RARARARBRARGADORA3PPARA | |
| SCHEMBL11568432 | 0.89 | HSD11B1 (0.52) | PSMB5HSD11B1RARARARBRARG | |
| SCHEMBL27730914 | 0.86 | PSMB5 (0.42) | PSMB5HSD11B1RARBADORA3PPARA | |
| SCHEMBL28804323 | 0.85 | PPARA (0.49) | PSMB5HSD11B1ADORA3PPARA | |
| SCHEMBL10802840 | 0.85 | PPARA (0.46) | PSMB5HSD11B1TYRPPARATLR8 | |
| SCHEMBL15391163 | 0.85 | PPARA (0.49) | PSMB5HSD11B1ADORA3PPARA | |
| SCHEMBL12610868 | 0.85 | PPARA (0.49) | PSMB5HSD11B1ADORA3PPARA | |
| SCHEMBL10802846 | 0.85 | PPARA (0.46) | PSMB5HSD11B1TYRPPARATLR8 | |
| SCHEMBL10661755 | 0.84 | PSMB5 (0.44) | PSMB5HSD11B1TYRADORA3 | |
| SCHEMBL8184843 | 0.83 | TYR (0.46) | HSD11B1TYRRARBADORA3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292462-A | INSULATORS-COOLANTS FOR TRANSFORMERS | RHONE-POULENC INDUSTRIES (FR) | 1981-09-29 | — | — | US | disclosed |
| US-4177156-A | SPECIALTY OILS FOR TRANSFORMERS | RHONE-POULENC INDUSTRIES (FR) | 1979-12-04 | — | — | US | disclosed |
| US-4119555-A | COOLANTS FOR TRANSFORMERS | RHONE-POULENC INDUSTRIES (FR) | 1978-10-10 | — | — | US | disclosed |