Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 3/20 | 0.45 |
| ▸ | RARA | P10276 | 3/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12467612 | 0.85 | HDAC1 (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL6746180 | 0.85 | HDAC1 (0.57) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL9593493 | 0.84 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL6770006 | 0.81 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL11318229 | 0.80 | HDAC1 (0.50) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL11319049 | 0.78 | SMYD3 (0.51) | HDAC1HDAC2KMT2APKMTSHR | |
| SCHEMBL12465787 | 0.76 | HDAC1 (0.47) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL9592333 | 0.75 | RARA (0.59) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL6770058 | 0.73 | HDAC3 (0.48) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL6770057 | 0.73 | HDAC3 (0.48) | HDAC1HDAC6HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258185-A | HYPOTENSIVE, ANTITHROMBOTIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1981-03-24 | — | — | US | disclosed |