⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160863 | 0.80 | THRB (0.34) | — | |
| SCHEMBL1412705 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL2160934 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL295125 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL8056794 | 0.73 | — | — | |
| SCHEMBL45482 | 0.72 | THRB (0.36) | — | |
| SCHEMBL4486956 | 0.72 | — | — | |
| SCHEMBL24470037 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL13616508 | 0.70 | THRB (0.35) | — | |
| SCHEMBL7113288 | 0.70 | THRB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010748-B1 | Diesel fuel antifoam composition | MOMENTIVE PERFORMANCE MAT INC (US) | 2011-02-16 | — | — | EP | claimed |
| EP-2223989-A1 | Diesel fuel antifoam composition | General Electric Company (US) | 2010-09-01 | — | — | EP | claimed |
| US-6093222-A | SYNERGISTIC BLEND OF LOW TO MODERATE MOLECULAR WEIGHT SILICONE WHICH ARE MORE SOLUBLE IN THE BLEND OF ADDITIVES ADDED TO THE PETROLEUM PRODUCT AT A REFINERY; MOTOR VEHICLE ENGINES; HYDROSILATED POLYSILOXANES; POLYETHERSILOXANES | CK WITCO CORPORATION (US) | 2000-07-25 | — | — | US | claimed |
| EP-1010748-A1 | Diesel fuel antifoam composition | CK WITCO CORPORATION (US) | 2000-06-21 | — | — | EP | claimed |
| US-9944823-B2 | Electrical insulation enamels composed of modified polymers and electrical conductors produced therefrom and having improved sliding capacity | SCHWERING & HASSE ELEKTRODRAHT GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| US-20130153261-A1 | Electrical Insulation Enamels Composed of Modified Polymers and Electrical Conductors Produced Therefrom and Having Improved Sliding Capacity | SCHWERING & HASSE ELEKTRODRAHT GMBH (DE) | 2013-06-20 | — | — | US | disclosed |