Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334176 | 0.84 | ALDH1A1 (0.59) | ALDH1A1IDO1POLBGAANPSR1 | |
| SCHEMBL7533794 | 0.81 | ALDH1A1 (0.66) | ALDH1A1IDO1POLBGAANPSR1 | |
| SCHEMBL22995206 | 0.81 | ALDH1A1 (0.56) | ALDH1A1IDO1POLBGAANPSR1 | |
| SCHEMBL11320932 | 0.81 | ALDH1A1 (0.56) | ALDH1A1IDO1POLBGAANPSR1 | |
| Hydrochloric Acid SCHEMBL11056062 | 0.79 | ALDH1A1 (0.63) | ALDH1A1IDO1POLBGAANPSR1 | |
| SCHEMBL1048060 | 0.78 | POLB (0.61) | ALDH1A1IDO1POLBGAANPSR1 | |
| SCHEMBL5800499 | 0.77 | ALDH1A1 (0.51) | ALDH1A1IDO1POLBGAANPSR1 | |
| SCHEMBL22995217 | 0.77 | ALDH1A1 (0.47) | ALDH1A1IDO1POLBGAANPSR1 | |
| SCHEMBL3397586 | 0.75 | ALDH1A1 (0.62) | ALDH1A1IDO1POLBGAANPSR1 | |
| SCHEMBL9214713 | 0.75 | ALDH1A1 (0.68) | ALDH1A1IDO1POLBGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4113718-A | Basic azo dyes | CIBA-GEIGY CORPORATION (US) | 1978-09-12 | — | — | US | disclosed |
| US-4064136-A | FROM A NITRILE, AN ALCOHOL AND ORTHO-SUBSTITUTED AROMATIC AMINE | CIBA-GEIGY AG (CH) | 1977-12-20 | — | — | US | disclosed |